Lipopolysaccharide endotoxins.

Isolation of lipopolysaccharide endotoxin.

Endotoxins, generally produced by gram-negative bacteria, are responsible for harmful effects in many diseases. These toxic compounds of nonprotein nature are part of the intact bacterial cells as opposed to the protein exotoxins found in cell-free broth cultures. Reviews concerning endotoxins have been published by Burrows (l), and by Westphal et al. (2). This report deals with the isolation, ...

Interactions of the Complement System with Endotoxic Lipopolysaccharide: Consumption of Each of the Six Terminal Complement Components

Large amounts of each C'3, C'5, C'6, C'7, C'8, and C'9 were consumed when guinea pig serum was incubated with endotoxic lipopolysaccharide, zymosan, or preformed immune complexes. Since these C' components subserve several of the biological activities which follow the injection of endotoxins into experimental animals, these experiments support the hypothesis that certain biological effects indu...

Immunization against experimental Pseudomonas aeruginosa and Serratia marcescens keratitis. Vaccination with lipopolysaccharide endotoxins and proteases.

Rabbits vaccinated with lipopolysaccharide endotoxins or with purified protease preparations from Pseudomonas aeruginosa and Serratia marcescens before corneal challenge with the viable bacteria exhibited significantly less corneal damage than rabbits not vaccinated with the bacterial products. However, the rabbits vaccinated with the lipopolysaccharide endotoxin preparations were significantly...

Shock in Mice in Lipopolysaccharide-Induced Endotoxin Production from Macrophages In Vitro and Augments Proinflammatory Cytokine Corticotropin-Releasing Hormone

Immune responses to lipopolysaccharide in relation to allergic disease, a TLR4 gene polymorphism and endotoxin exposure

___________________________________________________ 5 Sammanfattning_____________________________________________ 7 Abbreviations _______________________________________________ 9 Aims of the thesis __________________________________________ 1

Direct Interaction with Lipopolysaccharide C1 Inhibitor Prevents Endotoxin Shock Via a